BDBM50232549 CHEMBL4092846

SMILES OC(=O)c1ccc(CNC(=O)c2cc(F)ccc2Oc2ccc(F)cc2)cc1

InChI Key InChIKey=MKIRDUSAXONEOR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50232549   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232549(CHEMBL4092846)
Affinity DataIC50:  124nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232549(CHEMBL4092846)
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonist activity at human EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232549(CHEMBL4092846)
Affinity DataIC50:  236nMAssay Description:Antagonist activity at human EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232549(CHEMBL4092846)
Affinity DataIC50:  317nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232549(CHEMBL4092846)
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonist activity at human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed