BDBM50232637 CHEMBL4061274

SMILES CN(C)CCCCCN(C)C1=Nc2c(F)cc(F)cc2C(CC(=O)NCc2ccccc2)N1c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=HXAIKCGBLJLXQU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50232637   

TargetCholinesterase(Horse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50232637(CHEMBL4061274)
Affinity DataIC50: 380nMAssay Description:Inhibition of equine serum BCHE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50232637(CHEMBL4061274)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50232637(CHEMBL4061274)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human Cav3.2 alpha1H expressed in HEK tsA-201 cells at holding potential of -110 mV by whole cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed