BDBM50232773 CHEMBL4091670

SMILES NC(=N)c1ccc(cc1)\N=N\c1c(N)ncc2ccc(Br)cc12

InChI Key InChIKey=PRXMOIVSQYWNNZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50232773   

TargetNT-3 growth factor receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50232773(CHEMBL4091670)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human TrkC using poly[Glu:Tyr] (4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 2 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50232773(CHEMBL4091670)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 2 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2019
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50232773(CHEMBL4091670)
Affinity DataIC50: 19nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 2 hrs by Hotspot ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2019
Entry Details Article
PubMed