BDBM50232777 CHEMBL4102902

SMILES Oc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2ncccc12

InChI Key InChIKey=JKEWQEZHKJUJJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232777   

TargetSerine/threonine-protein kinase pim-1(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50232777(CHEMBL4102902)
Affinity DataIC50: 2nMAssay Description:Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50232777(CHEMBL4102902)
Affinity DataIC50: 420nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PIM2 (1 to 311 residues) expressed in baculovirus infected sf21 cells using S6K2 pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2019
Entry Details Article
PubMed