BDBM50233318 CHEMBL4090936

SMILES Cc1ccc(c(c1)C(=O)N1C[C@]2(C)CN(C[C@]2(C)C1)c1nc2cc(Cl)ccc2o1)-n1nccn1

InChI Key InChIKey=NVRQWYCSZKIPQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233318   

TargetOrexin/Hypocretin receptor type 1(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50233318(CHEMBL4090936)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at human orexin 1 receptor expressed in HEK293 cells assessed as inhibition of orexin-induced calcium mobilization after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2019
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50233318(CHEMBL4090936)
Affinity DataIC50: 5.99E+3nMAssay Description:Antagonist activity at human orexin 2 receptor expressed in HEK293 cells assessed as inhibition of orexin-induced calcium mobilization after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2019
Entry Details Article
PubMed