BDBM50233322 CHEMBL4090932

SMILES [H][C@@]12CN(C[C@]1([H])CN(C2)c1nc2cc(Cl)ccc2s1)C(=O)c1cc(C)ccc1-n1nccn1

InChI Key InChIKey=FTHYBOBONAKUHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233322   

TargetOrexin/Hypocretin receptor type 1(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50233322(CHEMBL4090932)
Affinity DataIC50: 327nMAssay Description:Antagonist activity at human orexin 1 receptor expressed in HEK293 cells assessed as inhibition of orexin-induced calcium mobilization after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2019
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50233322(CHEMBL4090932)
Affinity DataIC50: 1.19E+3nMAssay Description:Antagonist activity at human orexin 2 receptor expressed in HEK293 cells assessed as inhibition of orexin-induced calcium mobilization after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2019
Entry Details Article
PubMed