BDBM50233425 CHEMBL4063847

SMILES CN(C)c1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O

InChI Key InChIKey=KYIHGCYWLVORRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233425   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50233425(CHEMBL4063847)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2019
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50233425(CHEMBL4063847)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human N-terminal His-tagged IDO1 expressed in Escherichia coli using D-Trp as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2019
Entry Details Article
PubMed