BDBM50233426 CHEMBL4064144

SMILES O\N=C(/Nc1ccc(F)c(Br)c1)c1nonc1NCc1ccccc1

InChI Key InChIKey=XTEBFDOOXBYXAZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233426   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50233426(CHEMBL4064144)
Affinity DataIC50: 230nMAssay Description:Inhibition of human N-terminal His-tagged IDO1 expressed in Escherichia coli using D-Trp as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2019
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50233426(CHEMBL4064144)
Affinity DataIC50: 280nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2019
Entry Details Article
PubMed