BDBM50233482 CHEMBL4072719

SMILES COc1cc(ccc1Cl)C1OCCc2nc(SCc3c(F)cccc3Cl)n(c12)-c1ccc(F)cc1

InChI Key InChIKey=VTBSTZLAMQZJGA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233482   

TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50233482(CHEMBL4072719)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at TGR5 in human NCI-H716 cells assessed as increase in cAMP accumulation after 40 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50233482(CHEMBL4072719)
Affinity DataEC50:  778nMAssay Description:Agonist activity at TGR5 in mouse STC1 cells assessed as increase in cAMP accumulation after 40 mins by mass spectrometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed