BDBM50233513 CHEMBL4061329

SMILES COc1ccc(cc1OC)C1(C)CCCc2nc(SCc3c(F)cccc3Cl)n(c12)-c1ccc(F)cc1

InChI Key InChIKey=WLRUTEXWGKJCMI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233513   

TargetG-protein coupled bile acid receptor 1(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50233513(CHEMBL4061329)
Affinity DataEC50:  10nMAssay Description:Agonist activity at TGR5 in mouse STC1 cells assessed as increase in cAMP accumulation after 40 mins by mass spectrometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50233513(CHEMBL4061329)
Affinity DataEC50:  440nMAssay Description:Agonist activity at TGR5 in human NCI-H716 cells assessed as increase in cAMP accumulation after 40 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed