BDBM50233806 CHEMBL4102185::US11021454, Compound 6a

SMILES OC(=O)[C@H](Cc1ccc(O)c(O)c1)NC(=O)\C=C\c1ccc(O)c2oc(cc12)-c1ccc(O)c(O)c1

InChI Key InChIKey=XPOIVNVEXHJMNH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50233806   

TargetXanthine dehydrogenase/oxidase(Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM50233806(CHEMBL4102185 | US11021454, Compound 6a)
Affinity DataIC50: 4.52E+3nMAssay Description:12.1 Preparation of Reagents and Standard Solutions(1) Preparation of DPPH solution: accurately weigh the appropriate amount of DPPH, add MeOH and pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM50233806(CHEMBL4102185 | US11021454, Compound 6a)
Affinity DataIC50: 4.81E+3nMAssay Description:Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM50233806(CHEMBL4102185 | US11021454, Compound 6a)
Affinity DataIC50: 4.81E+3nMAssay Description:11.1 Preparation of Reagents and Standard Solutions(1) 75 mM phosphate buffer (PB, pH 7.4): containing KH2PO4 0.0956 g, K2HPO4 0.6946 g, EDTA 1.862 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent