BDBM50233893 CHEMBL4102420

SMILES Cc1csc2nc([nH]c(=O)c12)C(=O)NCc1cccc(NC(=O)CCc2nc[nH]n2)c1

InChI Key InChIKey=FOVJQTLLPOZKTJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50233893   

TargetCollagenase 3(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233893(CHEMBL4102420)
Affinity DataIC50: 0.290nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2019
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233893(CHEMBL4102420)
Affinity DataIC50: 76nMAssay Description:Inhibition of APMA-activated recombinant human MMP-8 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2019
Entry Details Article
PubMed
TargetStromelysin-2(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233893(CHEMBL4102420)
Affinity DataIC50: 270nMAssay Description:Inhibition of APMA-activated recombinant human MMP-10 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2019
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233893(CHEMBL4102420)
Affinity DataIC50: 670nMAssay Description:Inhibition of APMA-activated recombinant human MMP-2 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2019
Entry Details Article
PubMed