BDBM50233918 CHEMBL4063573

SMILES Cc1c(Sc2cccc(c2)C(O)=O)c2ccc(Cl)cc2n1C

InChI Key InChIKey=MZXTWQCBLHBIKZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50233918   

TargetAutotaxin(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50233918(CHEMBL4063573)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human ATX using bisP-nitrophenyl phosphate as substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50233918(CHEMBL4063573)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ATX (unknown origin) using lysophosphatidyl choline as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50233918(CHEMBL4063573)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells using LPC as substrate measured every 30 sec for 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2019
Entry Details Article
PubMed