BDBM50234079 CHEMBL4096048::US9701664, Example 80
SMILES Cc1ccc(NC(=O)c2ccc3OCCOc3c2)cc1NC(=O)c1ccc2NCCCc2c1
InChI Key InChIKey=LLTXIVYBCVSFHB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50234079
Affinity DataKi: 190nMAssay Description:Inhibition of bisamide probe binding to pirin in human SKOV3 cells by SILAC-based quantitative mass spectrometry pull down assayMore data for this Ligand-Target Pair
Affinity DataKd: 38nMAssay Description:Binding affinity to recombinant human pirin by surface plasma resonance methodMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
Affinity DataKd: 38nMAssay Description:Binding affinity to recombinant human pirin by surface plasma resonance methodMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair