BDBM50234092 CHEMBL4073637

SMILES OC(=O)[C@@H]1C[C@H](CN1)Oc1cccc(c1)C(O)=O

InChI Key InChIKey=HCIJBYYCGDXZCO-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50234092   

TargetGlutamate receptor ionotropic, kainate 1(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50234092(CHEMBL4073637)
Affinity DataKi:  3.31E+4nMAssay Description:Displacement of [3H]NF608 from eGFP-fused recombinant rat full length GluK1 receptor expressed in HEK293T/17 cells by liquid scintillation counting m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2019
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50234092(CHEMBL4073637)
Affinity DataKi:  3.60E+4nMAssay Description:Displacement of [3H]NF608 from eGFP-fused recombinant rat full length GluK1 receptor expressed in HEK293T/17 cells by liquid scintillation counting m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2019
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50234092(CHEMBL4073637)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]kainic acid from eGFP-fused recombinant rat full length GluK2 receptor expressed in HEK293T/17 cells by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2019
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50234092(CHEMBL4073637)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake after 15 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2019
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50234092(CHEMBL4073637)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake after 15 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2019
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50234092(CHEMBL4073637)
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]kainic acid from eGFP-fused recombinant rat full length GluK3 receptor expressed in HEK293T/17 cells by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2019
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 2(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50234092(CHEMBL4073637)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake after 15 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2019
Entry Details Article
PubMed