BDBM50234264 CHEMBL1326401

SMILES Oc1c(ccc2cccnc12)C(Nc1ccccn1)c1ccccc1F

InChI Key InChIKey=MUKYQISWKUJOTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234264   

TargetProtein disulfide-isomerase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50234264(CHEMBL1326401)
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) using bovine insulin as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
U.S. Army Medical Research Institute of Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50234264(CHEMBL1326401)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of protease activity of recombinant full length Clostridium botulinum Hall BoNT/A light chain using SNAP-25 peptide (187 to 203 residues) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed