BDBM50234365 CHEMBL4085709

SMILES COC(=O)\C=C\Oc1c(OC)cccc1[C@@H]1O[C@]2([C@H]([C@@H]1[N+]([O-])=O)c1ccc(Br)cc1)C(=O)N(Cc1ccccc1)c1ccccc21

InChI Key InChIKey=XHYJMCKLHBLVNY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234365   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234365(CHEMBL4085709)
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain expressed in Escherichia coli BL21-CodonPlus (DE3) using pNPP as substrate measured for 2 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234365(CHEMBL4085709)
Affinity DataIC50: 5.29E+3nMAssay Description:Inhibition of GST-tagged human SHP1 expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details Article
PubMed