BDBM50234454 CHEMBL2424832

SMILES NS(=O)(=O)c1ccc(CCN2C(=O)c3c(C2=O)c(Br)c(Br)c(Br)c3Br)cc1

InChI Key InChIKey=BZYJAFXEUBCXBJ-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50234454   

TargetCarbonic anhydrase 12(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234454(CHEMBL2424832)
Affinity DataKi:  10nMAssay Description:Inhibition of human membrane bound carbonic anhydrase 12 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234454(CHEMBL2424832)
Affinity DataKi:  16nMAssay Description:Inhibition of human membrane bound carbonic anhydrase 9 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234454(CHEMBL2424832)
Affinity DataKi:  77nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 7 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234454(CHEMBL2424832)
Affinity DataKi:  80nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234454(CHEMBL2424832)
Affinity DataKi:  185nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234454(CHEMBL2424832)
Affinity DataKi:  693nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 10 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234454(CHEMBL2424832)
Affinity DataKi:  2.39E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 10 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234454(CHEMBL2424832)
Affinity DataKi:  5.12E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 incubated for 10 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50234454(CHEMBL2424832)
Affinity DataKi:  8.84E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 incubated for 10 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2019
Entry Details Article
PubMed