BDBM50234481 1,2-dimethoxy-3-((2-(3-methoxyphenethyl)phenoxy)methyl)benzene::1-[(2,3-dimethoxybenzyl)oxy]-2-[2-(3-methoxyphenyl)ethyl]-benzene::CHEMBL258610

SMILES COc1cccc(CCc2ccccc2OCc2cccc(OC)c2OC)c1

InChI Key InChIKey=SBJIBBIMIYBVRK-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50234481   

TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234481(1,2-dimethoxy-3-((2-(3-methoxyphenethyl)phenoxy)me...)
Affinity DataEC50:  250nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234481(1,2-dimethoxy-3-((2-(3-methoxyphenethyl)phenoxy)me...)
Affinity DataIC50: 250nMAssay Description:Inhibition of ABCB1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234481(1,2-dimethoxy-3-((2-(3-methoxyphenethyl)phenoxy)me...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of ABCG2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234481(1,2-dimethoxy-3-((2-(3-methoxyphenethyl)phenoxy)me...)
Affinity DataEC50:  1.20E+5nMAssay Description:Inhibition of human BCRP pump mediated [3H]mitoxantrone transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed