BDBM50235250 CHEMBL4104525
SMILES O[C@H](C(c1cccnc1)c1cccnc1)c1cccnc1-c1cc(Cl)cc(Cl)c1
InChI Key InChIKey=ZRXWXSZEIJIKNS-QHCPKHFHSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50235250
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial myocytes by voltage-patch clamp electrophysiology methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in rapidly activating delayed rectifier cardiac potassium current by whole-cel...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of [3H]-MK499 from human ERG IKr channel expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of Kv1.5 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of Kv4.3 (unknown origin) assessed as reduction in transient outward potassium current by high throughput clamp methodMore data for this Ligand-Target Pair