BDBM50235277 CHEMBL4073977

SMILES CN(Cc1ccc2ccc(Cl)c(C3=C(C(=O)NC3=O)c3cn(C)c4ccccc34)c2c1)C1CC1

InChI Key InChIKey=SQVAWPTVROSMDK-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50235277   

TargetProtein kinase C beta type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235277(CHEMBL4073977)
Affinity DataIC50: 60nMAssay Description:Inhibition of PKCbeta1 (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2019
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235277(CHEMBL4073977)
Affinity DataIC50: 63nMAssay Description:Inhibition of PKCalpha (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2019
Entry Details Article
PubMed
TargetProtein kinase C eta type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235277(CHEMBL4073977)
Affinity DataIC50: 316nMAssay Description:Inhibition of PKCeta (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2019
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235277(CHEMBL4073977)
Affinity DataIC50: 316nMAssay Description:Inhibition of PKCepsilon (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2019
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235277(CHEMBL4073977)
Affinity DataIC50: 316nMAssay Description:Inhibition of PKCtheta (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2019
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235277(CHEMBL4073977)
Affinity DataIC50: 316nMAssay Description:Inhibition of PKCdelta (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2019
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235277(CHEMBL4073977)
Affinity DataIC50: 3.56E+3nMAssay Description:Inhibition of PKCtheta in human Jurkat T cells assessed as reduction in anti-CD3/CD28 antibody-induced T-cell activation by measuring decrease in IL-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2019
Entry Details Article
PubMed