BDBM50235290 CHEMBL4068028

SMILES CN1CCN(Cc2ccc3ccc(Cl)c(C4=C(C(=O)NC4=O)c4cn(C)c5ccccc45)c3c2)CC1

InChI Key InChIKey=BNAXHIOTDMDOLF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50235290   

TargetProtein kinase C beta type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235290(CHEMBL4068028)
Affinity DataIC50: 15nMAssay Description:Inhibition of PKCbeta1 (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2019
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235290(CHEMBL4068028)
Affinity DataIC50: 20nMAssay Description:Inhibition of PKCalpha (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2019
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235290(CHEMBL4068028)
Affinity DataIC50: 251nMAssay Description:Inhibition of PKCepsilon (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2019
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235290(CHEMBL4068028)
Affinity DataIC50: 292nMAssay Description:Inhibition of PKCdelta (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2019
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235290(CHEMBL4068028)
Affinity DataIC50: 314nMAssay Description:Inhibition of PKCtheta (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2019
Entry Details Article
PubMed
TargetProtein kinase C eta type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235290(CHEMBL4068028)
Affinity DataIC50: 316nMAssay Description:Inhibition of PKCeta (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2019
Entry Details Article
PubMed