BDBM50235401 CHEMBL4071823

SMILES COc1ccc2nc(CNC(=O)c3ccc(cc3)-c3cnccc3OCC3CCNCC3)[nH]c2c1

InChI Key InChIKey=WDTZIGXFNUJFSH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235401   

TargetMaternal embryonic leucine zipper kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235401(CHEMBL4071823)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of MELK (unknown origin) containing kinase domain and UBA domain using STK S1 as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2019
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235401(CHEMBL4071823)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2019
Entry Details Article
PubMed