BDBM50235509 CHEMBL399041::tert-butyl (R)-1-((R)-5-(cyclopropylmethyl)-2-oxo-1-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-ylamino)-1-oxo-3-(2-(trifluoromethyl)phenyl)propan-2-ylcarbamate

SMILES CC(C)(C)OC(=O)N[C@H](Cc1ccccc1C(F)(F)F)C(=O)N[C@@H]1CN(CC2CC2)c2ccccc2N(CC(F)(F)F)C1=O

InChI Key InChIKey=RNMVVTGLKPNLDF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235509   

TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50235509(tert-butyl (R)-1-((R)-5-(cyclopropylmethyl)-2-oxo-...)
Affinity DataIC50: 131nMAssay Description:Inhibition of human Nav1.7 sodium channel expressed in HEK293 cells by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed