BDBM50235517 CHEMBL254699::tert-butyl (R)-3-(2-fluorophenyl)-1-((R)-1-methyl-2-oxo-5-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-ylamino)-1-oxopropan-2-ylcarbamate

SMILES CN1c2ccccc2N(CC(F)(F)F)C[C@@H](NC(=O)[C@@H](Cc2ccccc2F)NC(=O)OC(C)(C)C)C1=O

InChI Key InChIKey=TXPYGHIWWSHOPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235517   

TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50235517(tert-butyl (R)-3-(2-fluorophenyl)-1-((R)-1-methyl-...)
Affinity DataIC50: 47nMAssay Description:Inhibition of human Nav1.7 sodium channel expressed in HEK293 cells by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed