BDBM50235597 CHEMBL4088968

SMILES Cc1c(C(=O)Nc2c(F)c(F)c(-c3ccccc3)c(F)c2F)c(O)nn1C

InChI Key InChIKey=YELPXAASZKFOBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235597   

TargetDihydrofolate reductase(Human)
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235597(CHEMBL4088968)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed