BDBM50235611 4-(3,3-diethyl-2,4-dioxoazetidin-1-yl)benzonitrile::CHEMBL272394

SMILES CCC1(CC)C(=O)N(C1=O)c1ccc(cc1)C#N

InChI Key InChIKey=HMFRNLRWFDIHSV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235611   

TargetNeutrophil elastase(Human)
University of Lisbon

Curated by ChEMBL
LigandPNGBDBM50235611(4-(3,3-diethyl-2,4-dioxoazetidin-1-yl)benzonitrile...)
Affinity DataKi:  63.5nMAssay Description:Inhibition of human leukocyte elastase after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
University of Lisbon

Curated by ChEMBL
LigandPNGBDBM50235611(4-(3,3-diethyl-2,4-dioxoazetidin-1-yl)benzonitrile...)
Affinity DataKi:  6.35E+4nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed