BDBM50235684 CHEMBL4100795

SMILES COc1ccc(cc1)-c1cc(nc2nc3n(nc(C(C)=O)n3c(=O)c12)-c1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1

InChI Key InChIKey=SMVILGFFGMAYRD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50235684   

TargetCarbonic anhydrase 9(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50235684(CHEMBL4100795)
Affinity DataKi:  330nMAssay Description:Inhibition of recombinant human tumor-associated carbonic anhydrase 9 assessed as inhibition of CO2 hydration preincubated for 15 mins prior to testi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50235684(CHEMBL4100795)
Affinity DataKi:  740nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 assessed as inhibition of CO2 hydration preincubated for 15 mins prior to testing by phenol red ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50235684(CHEMBL4100795)
Affinity DataKi:  3.01E+3nMAssay Description:Inhibition of recombinant human membrane-associated carbonic anhydrase 4 assessed as inhibition of CO2 hydration preincubated for 15 mins prior to te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50235684(CHEMBL4100795)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of recombinant human cytosolic carbonic anhydrase 1 assessed as inhibition of CO2 hydration preincubated for 15 mins prior to testing by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2019
Entry Details Article
PubMed