BDBM50235959 CHEMBL4064750

SMILES Cc1c(cc(CCO)n1-c1ccc(Cl)cc1C(F)(F)F)C(=O)Nc1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=GUKPXCNCKVJPOE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50235959   

TargetMineralocorticoid receptor(Human)
Instituto De Qu£Mica M£Dica (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50235959(CHEMBL4064750)
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at Gal4-fused human MR LBD (671 to 984 residues) expressed in African Green Monkey CV-1 cells assessed as inhibition of aldostero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Instituto De Qu£Mica M£Dica (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50235959(CHEMBL4064750)
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at Gal4-fused human MR LBD (671 to 984 residues) expressed in African Green Monkey CV-1 cells assessed as inhibition of aldostero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Instituto De Qu£Mica M£Dica (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50235959(CHEMBL4064750)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at Gal4-fused human MR LBD (671 to 984 residues) expressed in African Green Monkey CV-1 cells assessed as inhibition of aldostero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details Article
PubMed