BDBM50236144 CHEMBL4089935

SMILES CCCCNc1nc(N)nc(C)c1CCc1ccccc1

InChI Key InChIKey=RWMBDVJGYSHEFZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236144   

TargetToll-like receptor 8(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50236144(CHEMBL4089935)
Affinity DataEC50:  1.19E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2019
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50236144(CHEMBL4089935)
Affinity DataEC50:  2.82E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2019
Entry Details Article
PubMed