BDBM50236285 CHEMBL4098009

SMILES CC1(C)N=C(N)N=C(N)N1OCCCOc1cccc(c1)C(=O)C=Cc1ccccc1

InChI Key InChIKey=NQNOIYZAYVLVKV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50236285   

TargetDihydrofolate reductase(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236285(CHEMBL4098009)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human DHFR assessed as reduction in conversion of DHF to THF measured every 30 secs for 6 mins by UV-Vis spectrophotometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2019
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236285(CHEMBL4098009)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 60 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2019
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236285(CHEMBL4098009)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 30 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2019
Entry Details Article
PubMed