BDBM50236712 CHEMBL4069140

SMILES Fc1ccc(cc1)-c1c(cnc2cc(F)ccc12)S(=O)(=O)c1ccc(F)c(F)c1

InChI Key InChIKey=HEQJGGYLDWNFDT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236712   

TargetMetabotropic glutamate receptor 5(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50236712(CHEMBL4069140)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50236712(CHEMBL4069140)
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]M-MPEP from recombinant human mGluR5a expressed in human A18 cell membrane homogenate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed