BDBM50237078 CHEMBL256123::N-(6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfuran-2-yl)pyrimidin-4-yl)-2-(3-((ethylamino)methyl)phenoxy)acetamide

SMILES CCNCc1cccc(OCC(=O)Nc2cc(nc(n2)-c2ccc(C)o2)-n2nc(C)cc2C)c1

InChI Key InChIKey=JBRWEJMXORBYNB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50237078   

TargetAdenosine receptor A2a(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50237078(N-(6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfur...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50237078(N-(6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfur...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50237078(N-(6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfur...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed