BDBM50237149 CHEMBL4080424

SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1n[nH]c2cc(ccc12)-c1cccnc1

InChI Key InChIKey=AHGDPOCVDLPDGR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50237149   

TargetEpidermal growth factor receptor(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50237149(CHEMBL4080424)
Affinity DataIC50: 97nMAssay Description:Inhibition of wild-type human N-terminal GST-tagged EGFR cytoplasmic domain (669 to 1210 end amino acid residues) expressed in baculovirus expression...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50237149(CHEMBL4080424)
Affinity DataEC50:  5.67E+3nMAssay Description:Inhibition of wild-type EGFR in human A431 cells assessed as reduction in cell viability after 96 hrs by CellTiterGlo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2019
Entry Details Article
PubMed