BDBM50237220 CHEMBL4081906

SMILES CN1[C@H]([C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc3cc(Cl)ccc23)C11CCCCC1)c1nc(cs1)C(N)=O

InChI Key InChIKey=NTAXNQMOZQYSPY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50237220   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237220BDBM50237220(CHEMBL4081906)
Affinity DataKi:  20nMAssay Description:Inhibition of FAM-tagged p53-based PMDM6-F peptide binding to human recombinant His-tagged MDM2 (1 to 118 residues) after 30 mins by fluorescence pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2019
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237220BDBM50237220(CHEMBL4081906)
Affinity DataIC50: 156nMAssay Description:Inhibition of FAM-tagged p53-based PMDM6-F peptide binding to human recombinant His-tagged MDM2 (1 to 118 residues) after 30 mins by fluorescence pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2019
Entry Details Article
PubMed