BDBM50237237 CHEMBL4099920

SMILES OC(=O)c1cccc(Nc2c(nc3cnccn23)-c2cccc(O)c2)c1

InChI Key InChIKey=BKPMPSDRXIPBJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50237237   

TargetTyrosine-protein kinase SYK(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50237237(CHEMBL4099920 | US20250011330, Compound 7n)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of SYK (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition measured after 25 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Department Of Health and Human Services

US Patent
LigandPNGBDBM50237237(CHEMBL4099920 | US20250011330, Compound 7n)
Affinity DataIC50: 2.05E+6nMAssay Description:Table 1 and 2: TDP1 Gel-based in vitro assay was carried out as previously described Lountos, G. T., et al. (Nucleic Acids Res. (2019) 47(19) 10134-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent