BDBM50237284 CHEMBL4083281

SMILES [O-][N+](=O)c1cccc(c1)-c1nc2ccccc2n(Cc2ccco2)c1=O

InChI Key InChIKey=UMGZDFUNVVRTSB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50237284   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50237284(CHEMBL4083281)
Affinity DataEC50:  20nMAssay Description:Activation of human CFTR expressed in FRT cells co-expressing YFP H148Q mutant assessed as increase in forskolin-stimulated iodide influx measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2019
Entry Details Article
PubMed