BDBM50237746 CHEMBL4084744

SMILES O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3nc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F

InChI Key InChIKey=GGCMPMXRTAOSBN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50237746   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237746BDBM50237746(CHEMBL4084744)
Affinity DataKi:  13nMAssay Description:Inhibition of FAM-tagged p53-based PMDM6-F peptide binding to human recombinant His-tagged MDM2 (1 to 118 residues) after 30 mins by fluorescence pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2019
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237746BDBM50237746(CHEMBL4084744)
Affinity DataIC50: 51nMAssay Description:Inhibition of FAM-tagged p53-based PMDM6-F peptide binding to human recombinant His-tagged MDM2 (1 to 118 residues) after 30 mins by fluorescence pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2019
Entry Details Article
PubMed