BDBM50237854 CHEMBL255718::N-[5-(1,1-dioxo-1lambda*6*-isothiazolidin-2-yl)-1H-indazol-3-yl]-2-(4-hydroxy-phenyl)-acetamide

SMILES Oc1ccc(CC(=O)Nc2n[nH]c3ccc(cc23)N2CCCS2(=O)=O)cc1

InChI Key InChIKey=MEKQZIRNPYPHGO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50237854   

TargetCyclin-dependent kinase 2(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50237854(N-[5-(1,1-dioxo-1lambda*6*-isothiazolidin-2-yl)-1H...)
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50237854(N-[5-(1,1-dioxo-1lambda*6*-isothiazolidin-2-yl)-1H...)
Affinity DataIC50: 28nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50237854(N-[5-(1,1-dioxo-1lambda*6*-isothiazolidin-2-yl)-1H...)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed