BDBM50237935 CHEMBL4071624

SMILES COc1cc(c(F)cc1-n1c2ccc(cc2cnc1=O)S(=O)(=O)Nc1ccon1)-c1cccc(F)c1

InChI Key InChIKey=UKPHMXALYXDSIQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50237935   

TargetSodium channel protein type 9 subunit alpha(Human)
Moma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50237935(CHEMBL4071624)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of human Nav1.7 by PatchXpress assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Moma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50237935(CHEMBL4071624)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential yielding 20 to 50% inactivation measured after 3 to 5 mins by patchXpress e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50237935(CHEMBL4071624)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2019
Entry Details Article
PubMed