BDBM50238102 CHEMBL4065476

SMILES OC(c1ccccc1)c1cncnc1Nc1ccc(F)cc1

InChI Key InChIKey=PFPJEJXRUPCTAD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50238102   

TargetCytochrome P450 11B2, mitochondrial(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238102(CHEMBL4065476)
Affinity DataIC50: 30nMAssay Description:Inhibition of human CYP11B2 expressed in HEK293A cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238102(CHEMBL4065476)
Affinity DataIC50: 93nMAssay Description:Inhibition of human CYP11B1 expressed in HEK293A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238102(CHEMBL4065476)
Affinity DataIC50: 440nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed