BDBM50238109 CHEMBL4091167

SMILES CS(=O)(=O)N1CCC(CC1)C(O)c1cncnc1Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=WCOMYJCAEUEHRN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50238109   

TargetCytochrome P450 11B2, mitochondrial(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238109(CHEMBL4091167)
Affinity DataIC50: 3nMAssay Description:Inhibition of human CYP11B2 expressed in HEK293A cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238109(CHEMBL4091167)
Affinity DataIC50: 16nMAssay Description:Inhibition of human CYP11B1 expressed in HEK293A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238109(CHEMBL4091167)
Affinity DataIC50: 798nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed