BDBM50238812 CHEMBL4100201

SMILES COc1cc(OC)c(Cl)c(c1)-c1cc2cnc(NCC(O)CO)nc2n(CCc2ccc(NC(=O)C=C)cc2)c1=O

InChI Key InChIKey=JRUDYJIKCDGNFP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50238812   

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238812(CHEMBL4100201)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238812(CHEMBL4100201)
Affinity DataIC50: 37nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed