BDBM50239071 CHEMBL4101932

SMILES Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2nc(c(-c3ccccc3)c(Cl)c2c1)C(F)(F)F

InChI Key InChIKey=RWMDZUXSXDWAHA-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50239071   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50239071(CHEMBL4101932)
Affinity DataIC50:  120nMAssay Description:Tested for inhibition of thromboxane synthetase from spontaneously hypertensive ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50239071(CHEMBL4101932)
Affinity DataKd:  57nMAssay Description:Displacement of 1,8-ANS from recombinant human RORgammat LBD expressed in Escherichia coli BL21 (DE3) cells assessed as inhibition of co-activator SR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed