BDBM50239135 2-((3,4-dichlorophenyl)(methyl)amino)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone::CHEMBL402303

SMILES CN(CC(=O)N1CCC[C@@H]([C@@H]1CN1CCCC1)c1ccccc1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=HXWCQEQIPYCSAM-QPPBQGQZSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50239135   

TargetUrotensin-2 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50239135(2-((3,4-dichlorophenyl)(methyl)amino)-1-((2R,3R)-3...)
Affinity DataKi:  6nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50239135(2-((3,4-dichlorophenyl)(methyl)amino)-1-((2R,3R)-3...)
Affinity DataIC50:  800nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50239135(2-((3,4-dichlorophenyl)(methyl)amino)-1-((2R,3R)-3...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50239135(2-((3,4-dichlorophenyl)(methyl)amino)-1-((2R,3R)-3...)
Affinity DataEC50:  6.30E+3nMAssay Description:Agonist activity at kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed