BDBM50239166 CHEMBL4083411

SMILES Cc1nn2c(O)cc(nc2c1-c1ccc(F)cc1)C1CCN(CC1)C(=O)c1ccc(Br)nc1

InChI Key InChIKey=ZPEBUNDBUIAHKC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50239166   

TargetShort transient receptor potential channel 4(Mouse)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239166BDBM50239166(CHEMBL4083411)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at mouse TRPC4beta expressed in HEK293 cells co-expressing MOR decrease in DAMGO-evoked intracellular calcium level by Fluo-8-AM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Mouse)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239166BDBM50239166(CHEMBL4083411)
Affinity DataEC50:  1.23E+4nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed