BDBM50239321 CHEMBL4089579

SMILES N#Cc1cccc(Nc2nc(nc3ccccc23)-c2cccnc2)c1

InChI Key InChIKey=BYMLDJJNFGPNNT-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50239321   

LigandPNGBDBM50239321(CHEMBL4089579)
Affinity DataEC50:  85nMAssay Description:Inhibition of human GFP-fused ABCG2 expressed in MDCK2 cells assessed as potentiation of SN-38 induced cytotoxicity by measuring cell viability after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2019
Entry Details Article
PubMed
LigandPNGBDBM50239321(CHEMBL4089579)
Affinity DataIC50: 108nMAssay Description:Inhibition of recombinant human GFP-fused ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux preincubated for 30 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2019
Entry Details Article
PubMed
LigandPNGBDBM50239321(CHEMBL4089579)
Affinity DataEC50:  350nMAssay Description:Activation of ABCG2 (unknown origin) ATPase activity expressed in baculovirus infected high five cell membranes by ascorbic acid/ammonia molybdate re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2019
Entry Details Article
PubMed