BDBM50239406 CHEMBL4091507

SMILES Oc1ccc(N2CCCN(CCCCOc3ccn4nccc4c3)CC2)c2ccc(=O)[nH]c12

InChI Key InChIKey=TYDUDPVGSUDIDV-UHFFFAOYSA-N

Data  7 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50239406   

TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-Nuernberg

Curated by ChEMBL
LigandPNGBDBM50239406(CHEMBL4091507)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]spiperone from human D3R expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-Nuernberg

Curated by ChEMBL
LigandPNGBDBM50239406(CHEMBL4091507)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]spiperone from human D2SR expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-Nuernberg

Curated by ChEMBL
LigandPNGBDBM50239406(CHEMBL4091507)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]spiperone from human D2LR expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-Nuernberg

Curated by ChEMBL
LigandPNGBDBM50239406(CHEMBL4091507)
Affinity DataEC50:  90nMAssay Description:Agonist activity at human D2S receptor expressed in HEK293T cell membranes coexpressing Galphao1 assessed as induction of nucleotide exchange preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-Nuernberg

Curated by ChEMBL
LigandPNGBDBM50239406(CHEMBL4091507)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]spiperone from human D4R expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-Nuernberg

Curated by ChEMBL
LigandPNGBDBM50239406(CHEMBL4091507)
Affinity DataEC50:  250nMAssay Description:Partial agonist activity at human D2SR expressed in HEK293T cells co-expressing (EA)beta-arrestin2 and GRK2 assessed as induction of beta-arrestin2 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-Nuernberg

Curated by ChEMBL
LigandPNGBDBM50239406(CHEMBL4091507)
Affinity DataEC50:  370nMAssay Description:Partial agonist activity at human D2SR expressed in HEK293T cells co-expressing (EA)beta-arrestin2 assessed as induction of beta-arrestin2 recruitmen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Friedrich-Alexander University Erlangen-Nuernberg

Curated by ChEMBL
LigandPNGBDBM50239406(CHEMBL4091507)
Affinity DataKi:  9.00E+3nMAssay Description:Displacement of [3H]ketanserin from human 5-HT2AR expressed in HEK293T cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-Nuernberg

Curated by ChEMBL
LigandPNGBDBM50239406(CHEMBL4091507)
Affinity DataKi:  1.30E+4nMAssay Description:Displacement of [3H]SCH23390 from human D1R expressed in HEK293T cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-Nuernberg

Curated by ChEMBL
LigandPNGBDBM50239406(CHEMBL4091507)
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of [3H]SCH23390 from human D5R expressed in HEK293T cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed