BDBM50239773 CHEMBL492244

SMILES CN1CCN(CCON=C2C(Nc3ccccc23)=C2C(=O)Nc3cc(Br)ccc23)CC1

InChI Key InChIKey=UWZGPKLUCAHSOA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50239773   

TargetGlycogen synthase kinase-3 beta(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239773(CHEMBL492244)
Affinity DataIC50: 5nMAssay Description:Inhibition of human N-terminal GST/His6-tagged GSK3beta (M1 to T420 residues) expressed in baculovirus infected sf9 cells using RBER-IRStide as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239773(CHEMBL492244)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged CDK1 (M1 to M297 residues)/Cyclin B1 (M1 to V433 residues) expressed in sf9 cells using RB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239773(CHEMBL492244)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK5 (M1 to P292 residues)/p35NCK (M1 to R307 residues) expressed in baculovirus infected sf9 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed