BDBM50239776 CHEMBL4085289

SMILES COc1ccc2NC(=O)\C(=C3\Nc4ccccc4\C\3=N/OCCO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2c1

InChI Key InChIKey=OXFMTURCMJXJOI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50239776   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239776(CHEMBL4085289)
Affinity DataIC50: 90nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinE expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239776(CHEMBL4085289)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant GSK3beta (unknown origin) after 10 mins in presence of [gamma32P]ATP by beta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239776(CHEMBL4085289)
Affinity DataIC50: 410nMAssay Description:Inhibition of full length human N-terminal His6-tagged CDK6/N-terminal GST-tagged CyclinD3 expressed in sf21 cells after 10 mins in presence of [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239776(CHEMBL4085289)
Affinity DataIC50: 840nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinA expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239776(CHEMBL4085289)
Affinity DataIC50: 5.58E+3nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK1/N-terminal GST-tagged CyclinB expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed